Figure 1 summarizes all pipeline products currently in Phase I, II, and III for bronchiectasis within the three major markets (3MM: the US, Germany, and the UK). Some people who perform CPT find it hard or uncomfortable to do. doi: 10.1002/ccr3.6378. Epub 2019 Jan 16. Disclaimer. 212-305-5730. Your doctor may recommend surgery if the bronchiectasis is isolated to a section of lung, or you have a lot of bleeding. The goals of . We present an approach to the multi-biome that integrates bacterial, viral . Please enable it to take advantage of the complete set of features! This trial is testing if a drug called benralizumab can help reduce exacerbation rates for people with non-cystic fibrosis bronchiectasis who also have eosinophilic inflammation. Session 4: New treatments. If you think your loved one might be struggling with his/her condition reach out and encourage them to seek expert help. Treatment for bronchiectasis is designed to prevent lung infections and reduce or prevent exacerbations (flareups). These data are in agreement with other recent publications that have also demonstrated the great economic burden related to bronchiectasis. Offer patients with bronchiectasis associated with clinical deterioration and a new growth of P. aeruginosa (1st isolation or regrowth in the context of intermittently positive cultures) eradication antibiotic treatment. Official websites use .gov DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. Bookshelf Your doctor may recommend surgery if no other treatments have helped and only one part of your airway is affected. Rev Pneumol Clin. Uses, Side Effects, & Dosage, What is Incruse Ellipta? While more research and clinical trials are needed, the top-line results of this study highlight the tremendous value of clinical trials in providing patients with access to more effective, simpler treatments. This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. It is important to emphasise that in this present study, only patients who had hospitalisations related to bronchiectasis were included. official website and that any information you provide is encrypted Maintain a healthy diet, low in sodium, added sugars, saturated fats and refined grains. Several devices can help with CPT, such as: Several breathing techniques are also used to help move mucus to the upper airway so it can be coughed up. Epub 2014 Jan 13. There have been no previous international guidelines. Until a few decades ago, bronchiectasis was considered an . But with proper care and treatment, you can manage it. Bronchiectasis often is treated with medicines, hydration, and chest physical therapy (CPT). I was diagnosed with bronchiectasis about the time that Covid hit the US and the pulmonologist are overworked, so I have lots of unanswered questions. In a . Although understanding of the pathophysiology of bronchiectasis is at an early stage, we argue that bronchiectasis is a heterogeneous disease with many different biological mechanisms that drive disease progression (endotypes), and therefore the so-called treatable traits approach used in asthma and chronic obstructive pulmonary disease could be applied to bronchiectasis, with future trials targeted at the specific disease subgroups most likely to benefit. Uses, Side Effects, & Dosage, What is Wixela Inhub? The site is secure. Chronic obstructive pulmonary disease (COPD) is a chronic lung condition characterized by shortness of breath, cough and sputum production due to both airway and parenchymal lung damage. Bronchiectasis is a lung condition that causes a persistent cough and excess phlegm, or sputum. Share your voice and advocate for policies that will save lives. HHS Vulnerability Disclosure, Help This website uses cookies to improve content delivery. Bronchiectasis is a clinical syndrome characterized by cough and sputum production in the presence of abnormal thickening and dilation of the bronchial wall that is visible on lung . Thank you! Bronchiectasis often is treated with medicines, hydration, and chest physical therapy (CPT). The authorities have not yet approved it for the treatment. 13 In a prospective study of 69 children followed for 900 child-months, 36 exacerbations . These tests include: The doctor collects a small amount of sputum (spit) to check for any viruses, bacteria or other microorganisms. Our team has extensive experience diagnosing and treating different types of bronchiectasis and related conditions, including non . 2021 Feb;246(3):275-280. doi: 10.1177/1535370220972324. Clinical Trial Guide for Seniors and the Elderly, Clinical Trial Guide for Parents and Children, Guide To Keeping Your Health Records Secure, Clinical Trials on the Effects of Bullying, Clinical Trials on the Positive Effects of Gardening and Experiencing Nature, Clinical Trials on the Disaster Mental Health, A Guide to Bronchiectasis and Clinical Trials, https://www.bmj.com/rapid-response/2011/11/01/role-pneumococcal-and-influenza-vaccination-management-bronchiectasis, https://www.nhlbi.nih.gov/health-topics/bronchiectasis, https://www.lung.org/lung-health-and-diseases/lung-disease-lookup/bronchiectasis/diagnosing-and-treating.html. for Pulmonary Mycobacterium Avium Complex (MAC) Infection. But there is hope - our Clinical Trials Unit is Read More The website, developed , Medical management of bronchiectasis: more MDT would help Patients with bronchiectasis may be missing out on some aspects of best practice care, according to a , Respiratory follow-up to improve outcomes for Aboriginal children: twelve key steps. It is designed that from 2021 Q4 to 2022 Q2, 1,250 bronchiectasis patients . Accessibility Clipboard, Search History, and several other advanced features are temporarily unavailable. new treatments for bronchiectasis 2021. It covers the pipeline drug profiles, including clinical and nonclinical stage products. 8600 Rockville Pike This trial is testing a new medication for bronchiectasis called ARINA-1. Martnez-Garca M, Oscullo G, Garca-Ortega A, Matera MG, Rogliani P, Cazzola M. Drugs. 2022. Study Summary. I was diagnosed with MAI/MAC about 12 years ago. ronchiectasis is a disease of the lungs that causes damaged airways to permanently dilate. They often are combined with decongestants, which may provide extra relief. New therapeutic options for Non-cystic Fibrosis Bronchiectasis treatment as 5+ companies are working for the drug profiles. Want updates on the latest lung health news, including COVID-19, research, inspiring stories and health information? Learn more about bronchiectasis symptoms, causes, diagnosis, and treatment. This trialaims to improve MRI imaging of lungs using special contrast agents and coils tuned to their frequencies. The risk of developing bronchiectasis increases with age. Clipboard, Search History, and several other advanced features are temporarily unavailable. Objective To explore the . To ensure these treatments achieve success in randomised clinical trials-and therefore reach patients-we propose a reassessment of the current approach to bronchiectasis. The incidence of bronchiectasis increases substantially with age, from 2 per 100,000 persons aged 18 to 34 years to 154 per 100,000 persons aged 75 . It is a permanent condition that gets worse over time. This trial will test a new device that monitors heart rate, breathing rate, temperature, cough, and activity to see if it can predict worsening or increasing severity of lung conditions. Another important aspect related to bronchiectasis expenses is that the greater the severity of the disease, the higher its healthcare costs. A new website, called Strong Lungs, has been launched that is specifically designed for Aboriginal and Torres Strait Islander adults with bronchiectasis. Oxygen poses a fire risk, so you should never smoke or use flammable materials when using oxygen. Bronchiectasis is an irreversible widening (dilation) of portions of the breathing tubes or airways (bronchi) resulting from damage to the airway wall. Bronchiectasis is growing in prevalence and there are limited treatment options available. We do not capture any email address. Management. It typically occurs with other symptoms. Doing this helps loosen the mucus from your lungs so you can cough it up. FOIA Stay hydrated, drinking plenty of water to help prevent mucus build-up. Numerous diseases and external insults may trigger the process of developing bronchiectasis, which makes the management of this disease even more challenging [1]. 2 The British Thoracic Society guideline for bronchiectasis in adults was published in 2019. The trial will measure the safety and efficacy of ARINA-1 by looking at quality of life, sputum rheological markers, and blood inflammatory markers. Pamela Laird et al. These tests are performed to determine if the lungs are functioning properly. B. ronchiectasis is a disease of the lungs that causes damaged airways to permanently dilate. For people with bronchiectasis, the symptoms and exacerbations of the disease can have a debilitating impact on their quality of life. New research opportunity for people with mild cognitive impairment or early stage Alzheimer's. Disclaimer. Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand Thoracic Society of Australia and New Zealand guidelines. The overlap between bronchiectasis and chronic airway diseases: state of the art and future directions. The Nontuberculous Mycobacteria (NTM) Australia Research Network is brought Greenslopes Private Hospital, Newdegate Street, Greenslopes QLD 4120, Studies Seeking Recruitment: Clinical Trials, Studies Seeking Recruitment: Veteran Health. Unauthorized use of these marks is strictly prohibited. Bronchiectasis exacerbations are currently understood to be . There is an urgent need for new treatments and these trial results represent a significant step forward in addressing this problem. 3 Around one in five people with COPD die within one year of their first . We are excited by the positive top-line results recentlyannounced from one of our clinical trials into a new treatment for bronchiectasis. Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. This can be downloaded from: LFA Bronchiectasis Action Plan, Lung Foundation Australia have excellent COVID 19 resources on their website collated from information provided by the Australian Government Department of Health and leading respiratory , Interview with Infectious diseases expert, Prof James Chalmers. Our service is free and we are here to help you. What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, and significant licensing activities that will impact the NCFBE market? Key points included are related to imaging, in whom a , After publishing the first guidelines in the world on the diagnosis and management of bronchiectasis back in 2008, the Spanish Society of Pulmonology (SEPAR) have , Vitamin D is a key molecule known to be involved in inflammation and immune responses so a team of Italian researchers sought to investigate whether , Inhaledantibioticshave been proposed as efficient treatments to reduce bacterial infections inbronchiectasispatients. Avoid strong smells and lung irritants such as dust, smoke, and fumes. If you are feeling overwhelmed, talk to someone. Oxygen therapy can be given for a short or long period of time in the hospital, in another medical setting, or at home. , Pulmonology By Valencia Higuera Updated on Oct 4, 2021 Current treatments MeSH Uses, Side Effects, & Dosage. Eur Respir J. All of our trials are run by licensed doctors, researchers, and healthcare companies. The American Lung Association is a 501(c)(3) charitable organization. Am I at more risk of getting COVID-19 than somebody , A recent paper in Respiratory Medicine has shown that the prevalence and incidence of bronchiectasis in the UK is increasing, with a 3% increase in , Results from the Australian Bronchiectasis Registry (ABR) show a gap between guideline recommendations and real-world treatment of bronchiectasis, even in tertiary centres. Session 2: Self-management of bronchiectasis. The trial will last 28 days, and participants will be randomly assigned to either take ARINA-1 or a placebo twice daily. Bronchiectasis is dilation and destruction of larger bronchi caused by chronic infection and inflammation. The incidence rate of bronchiectasis increased sharply with age for both men and women, as previously described [4]. During an exacerbation, the patient experiences at least three of the following symptoms: Though there is no cure for bronchiectasis, treatments exist to alleviate symptoms and prevent exacerbations. Congenital bronchiectasis happens when the lungs develop abnormally in utero. Share sensitive information only on official, secure websites. When facing a disease as heterogeneous as bronchiectasis is, we should expect different results according to countries and regions. Development of new treatments is needed urgently. Patients with chronic lung diseases are more prone to emotional problems such as anxiety and depression. Learn to recognize what might trigger an exacerbation event so you are always prepared and able to act fast. Be diligent about taking oral and inhaled medications and performing mucus clearance techniques daily. Respiratory physiotherapy in the bronchiectasis guidelines: is there a loud voice we are yet to hear? Though they may be beneficial for some people, they are only used in the most severe situations because they have extreme side-effects. Surgery may be recommended in extreme situations where the bronchiectasis is isolated to a section of lung or there is excessive bleeding. This trial is testing if a drug called benralizumab can help reduce exacerbation rates for people with non-cystic fibrosis bronchiectasis who also have eosinophilic inflammation. 81925001/National Natural Science Fund for Distinguished Young Scholar, 202101070007-E00097/Innovation Program of Shanghai Municipal Education Commission. DelveInsight's Non-Cystic Fibrosis Bronchiectasis (NCFB) - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Non-Cystic Fibrosis Bronchiectasis (NCFB) in the United States, EU5 (Germany, Spain, Italy, France and the United Kingdom), and Japan. In addition, sociodemographic characteristics may differ across regions. Acta Biochim Biophys Sin (Shanghai). Now researchers have shown that a new formulation of antibiotics using nanoparticles, called nanoplex, , The latest European Respiratory Society Monograph: Bronchiectasis is now available! Bronchiectasis is a complex and heterogeneous condition characterised by persistent airway dilation, mucus hypersecretion, and recurrent respiratory infectious exacerbations. Federal government websites often end in .gov or .mil. Patients experience a persistent cough, sputum production, and recurrent infections, accompanied by the radiological findings of dilated and thickened bronchi. Uses, Side Effects, & Dosage, What is Tobi Podhaler? Unfortunately, this is still not reality for several South American, African and Asian countries [22]. Moreover, the proposal of new phenotype, measurement tools and predictors on bronchiectasis, promote the process of individualized therapy for patients. Pediatr Pulmonol. We only share your information with the clinical trials you're trying to access. Non-cystic Fibrosis Bronchiectasis Therapies Late-stage (Phase III), Non-cystic Fibrosis Bronchiectasis Therapies Early-stage (Phase I), NCFBE Pre-clinical stage and Discovery candidates. Epub 2016 Feb 3. Offer to help whenever you can and be understanding of their condition. (COPD). The U.S. Food and Drug Administration (FDA) has permitted breakthrough therapy designation for. Interventions for bronchiectasis: an overview of Cochrane systematic reviews. Tiotropium via HandiHaler is an established long-acting, anticholinergic bronchodilator that prevents exacerbations and improves lung function in patients with COPD. Scenario: COVID-19: Covers management when considering the possibility of COVID-19. Unable to load your collection due to an error, Unable to load your delegates due to an error. Bronchiectasis what are the stages and symptoms. and transmitted securely. Bronchiectasis is a chronic condition, meaning that there is no cure for it, however, there are treatments available that can help patients control and manage their symptoms. Chinese Medical Association Publishing House Ltd. doi: 10.3760/cma.j.cn112147-20220111-00036. This designation is given to therapies that show considerable . These patients also have high expenses related to their outpatient treatments [16, 17]. . Sign up today for your free Reader Account! Oxygen therapy may be recommended to raise low blood oxygen levels. This trial will study the effects of Trikafta on non-cystic fibrosis bronchiectasis sufferers, measuring clinical endpoints, quality of life and weight, plus collecting biopsy material to test cellular response. Mortality trends due to bronchiectasis have changed with time Burden Bronchiectasis causes significant anxiety and stress in children and their parents, especially during exacerbations, 12 some of which require hospitalization and increase economic burden. The global economic burden of bronchiectasis is far deeper than previously expected. No treatments have been licensed by regulatory agencies worldwide, and most therapies used in clinical practice are based on very little evidence. At the same time, an international expert consensus proposed radiological and clinical diagnosis criteria for inclusion of bronchiectasis patients in clinical trials. Several studies started to demonstrate a considerable increase in both the incidence and prevalence of this condition, especially in older populations [4]. eCollection 2022 Sep. Bronchiectasis: an update on current pharmacotherapy and future perspectives. One of the reasons attributed by the authors for this finding was the significant reduction in tuberculosis cases in Singapore in recent years [14], since Mycobacterium tuberculosis infection is a well-recognised cause of bronchiectasis. INS1007 is an investigational, first-in-class, oral, selective, reversible inhibitor of dipeptidyl peptidase I (DPP1) developed by Insmed to treat Non-cystic Fibrosis Bronchiectasis patients. For hard-to-treat infections, your doctor may prescribe intravenous (IV) antibiotics. 2018 Sep 15;52(3):1800328. doi: 10.1183/13993003.00328-2018. Dec. 03, 2021. Bronchiectasis describes the widening ("ectasis") of some of the airways. Accessibility The document summarised the epidemiology, pathogenesis, etiology, clinical diagnosis, treatment strategies and patient education of bronchiectasis in China according to a systematic review of the . This chronic, progressive respiratory disorder can cause persistent coughing and repeated infections. 2.2 Bronchiectasis Treatment Market Size across Key Geographies Worldwide: 2017 VS 2021 VS 2028 2.3 Global Bronchiectasis Treatment Market Size by Region (2017-2022) April 13, 2021 20:20 ET What are the current novel therapies, targets, mechanisms of action, and technologies developed to overcome the limitation of existing NCFBE therapies? This trial is testing whether or not the BCG vaccine can help adults with cystic fibrosis or non-cystic fibrosis bronchiectasis by boosting their immunity. Individual results may vary. Uses, Side Effects, & Dosage, What is Formoterol Fumarate? ACB is FET that involves deep breathing exercises. Bronchiectasis is growing in prevalence and there are limited treatment options available. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Inhaled Therapy Gets Breakthrough Designation for Non-Cystic Fibrosis Bronchiectasis. Oxygen therapy is a treatment that delivers oxygen for you to breathe. Chest Physical Therapy (CPT), or chest physiotherapy, is a popular respiratory therapist technique that involves clapping on the chest in a certain way that helps loosen mucus from the lungs so it can be expelled. Antibioticsare the most common treatment for bronchiectasis. This chronic, progressive respiratory disorder can cause persistent coughing and repeated infections. The study, Vitamin D , Lung Foundation Australia have recently updated their bronchiectasis action plan. It is interesting to note that there has been an average annual increase of 5.0% for inpatient cost per patient (USD 4032 in 2007 versus USD 6563 in 2017), which reflects the increasing complexity of treating these patients [14]. This way, therapeutic measures can be quickly implemented and, consequently, prevent the progression of bronchiectasis to more severe stages. Your doctor may recommend surgery if the bronchiectasis is isolated to a section of lung, or you have a lot of bleeding. We did a systematic review of scientific literature and clinical trial registries to identify agents in early-to-late clinical development for bronchiectasis in adults. New Search; Advanced Search; See Studies by Topic; See Studies on Map . PMC In 2021, a series of significant research progress have been made in bronchiectasis, focusing on the mechanism, diagnosis, clinical phenotypes, treatment, comorbidities, etc. Bronchiectasis has received increasing attention in recent years. During a pulmonary functioning test the doctor may have the patient breath in and out a tube with neutral and maximum effort to measure the volume of the lungs. A Narrative Review. 2022 Nov 25;54(11):1740-1747. doi: 10.3724/abbs.2022169. Provenance: Commissioned article, peer reviewed. Careers. Print 2017 Sep. Kelly C, Grundy S, Lynes D, Evans DJ, Gudur S, Milan SJ, Spencer S. Cochrane Database Syst Rev. Good hydration helps keep airway mucus moist and slippery and easier to cough up. Their first report, published in Respiratory Medicine (Australian , The British Thoracic Society have updated their recommendations and clinical practice points in January 2019. Los Angeles, USA, April 13, 2021 (GLOBE NEWSWIRE) -- Non-cystic Fibrosis Bronchiectasis Treatment 2021 | Prominent Players, Pipeline Growth, Future Trends, Unmet Demands, Emerging Therapies . An early diagnosis combined with optimal management offers the prospect, at least in some patients, of curing a . I was diagnosed with Bronchiectasis while I had severe pneumonia, a combination of Pseudomonas and MAC. The site is secure. Your tax-deductible donation funds lung disease and lung cancer research, new treatments, lung health education, and more. The clinical phenotype of bronchiectasis and its clinical guiding implications. All players (patients, healthcare professionals and payers) will benefit from this. European Respiratory Society guidelines for the management of adult bronchiectasis highlight the paucity of treatment options available for patients with this disorder. In addition, patients with bronchiectasis have higher hospital costs compared with matched controls [15, 16]. Before There are several online and in-person support groups for patients with bronchiectasis. Symptoms are chronic cough and purulent sputum expectoration; some patients may also have fever and dyspnea. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Bronchiectasis: moving from an orphan disease to an unpleasant socioeconomic burden, Human Regulatory. The treatment consisted of multiple, serial courses of antibiotics, inhalers, and duoneb nebs to open my lungs and an airway clearance device. The overall annual incidence of bronchiectasis is approximately 29 cases per 100,000 U.S. adults aged 18 years and older and is also higher for women (34 per 100,000) versus men (23 per 100,000). Respiratory Therapy, 12(1), 45-49. It is interesting to note that, as found by Phua et al. 10 Bronchiectasis Clinical Trials Near Me, Top Hospitals for Bronchiectasis Clinical Trials, University of Texas Health Science Center at Tyler, Cardiopulmonary rehabilitation post lung transplant, Top Cities for Bronchiectasis Clinical Trials, Bronchiectasis Clinical Trials by Phase of Trial, Bronchiectasis Clinical Trials by Age Group, Most Recent Bronchiectasis Clinical Trials, Top Treatments for Bronchiectasis Clinical Trials, Idiopathic Pulmonary Fibrosis Clinical Trials 2023, Interstitial Lung Disease Clinical Trials 2023, The Ultimate Guide to Understanding Cystic Fibrosis, A Guide To 7 Of The Most Common Genetic Disorder, What is Spiriva? The improvement and greater availability of diagnostic imaging methods associated with new studies aimed to understand the pathophysiology of bronchiectasis has opened a new chapter for this disease [3]. Join over 700,000 people who receive the latest news about lung health, including COVID-19, research, air quality, inspiring stories and resources. This site needs JavaScript to work properly. With acquired, or environmental bronchiectasis, damages to the airways can begin during childhood; however, a person might not develop any symptoms until many years later. JAMA. DelveInsights Non-cystic Fibrosis Bronchiectasis (NCFBE) Pipeline Insight report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in the Non-cystic Fibrosis Bronchiectasis pipeline landscapes. Print 2018 Sep. Respirology. These findings highlight the importance of local data in order to allow this complex scenario of bronchiectasis to be better understood while taking into account all particularities inherent to this pathology. Surgery may be recommended in extreme situations where the bronchiectasis is isolated to a section of lung or there . Polverino E, Goeminne PC, McDonnell MJ, Aliberti S, Marshall SE, Loebinger MR, Murris M, Cantn R, Torres A, Dimakou K, De Soyza A, Hill AT, Haworth CS, Vendrell M, Ringshausen FC, Subotic D, Wilson R, Vilar J, Stallberg B, Welte T, Rohde G, Blasi F, Elborn S, Almagro M, Timothy A, Ruddy T, Tonia T, Rigau D, Chalmers JD. Introduction. Bronchiectasis is an irreversible widening (dilation) of portions of the breathing tubes or airways (bronchi) resulting from damage to the airway wall. Australian adults with bronchiectasis: The first report from the Australian Bronchiectasis Registry, Updated British Thoracic Society guidelines, Updated Spanish guidelines on the treatment of bronchiectasis in adults, New Antibiotic Formulation Better at Controlling Infections in Bronchiectasis, New Guidelines on Managing Adult Bronchiectasis. However, in recent years, bronchiectasis has no longer been considered an orphan disease [2]. DPP1 is an enzyme held to activate neutrophil serine proteases (NSPs), such as neutrophil elastase, in neutrophils when formed in the bone marrow. This leads mucus build up in the patient's lungs, making it harder to breathe and creating a viable environment for bacteria and infections. For example, the average age of the bronchiectasis population in South America tends to be lower when compared to the European and North American population [23]. Bronchiectasis is a chronic disease that gets worse over time. You can search for clinical trials on the Lung Association's Clinical Trial Registry or ClinicalTrials.gov. In this Review, we discuss the mechanisms and potential roles of emerging therapies, including drugs that target airway and . Read the study Goyal V, Grimwood K, Marchant J, Masters IB, Chang AB. Nat Rev Dis Primers. Some of these devices are Oscillating Positive Expiratory Pressure (PEP), Intrapulmonary Percussive Ventilation (IPV) and Postural Drainage. Orphan Designation: Overview, Bronchiectasis in Germany: a population-based estimation of disease prevalence, Prevalence and incidence of bronchiectasis in Catalonia, Spain: a population-based study, Prevalence and incidence of noncystic fibrosis bronchiectasis among US adults in 2013, European Respiratory Society guidelines for the management of adult bronchiectasis, Brazilian consensus on non-cystic fibrosis bronchiectasis, Spanish guidelines on treatment of bronchiectasis in adults, Bronchiectasis: new therapies and new perspectives, Current and future pharmacotherapy options for non-cystic fibrosis bronchiectasis, Epidemiology and economic burden of bronchiectasis requiring hospitalisation in Singapore, Economic burden of non-cystic fibrosis bronchiectasis in the first year after diagnosis from a US health plan perspective, Economic burden of bronchiectasis in Germany, Cost of hospitalizations due to exacerbation in patients with non-cystic fibrosis bronchiectasis, Bronchiectasis-associated hospitalizations in Germany, 20052011: a population-based study of disease burden and trends, Time trends in hospital admissions for bronchiectasis: analysis of the Spanish national hospital discharge data (2004 to 2013), Trends and burden of bronchiectasis-associated hospitalizations in the United States, 19932006, A prospective cohort study of the use of domiciliary intravenous antibiotics in bronchiectasis, Latin America validation of FACED score in patients with bronchiectasis: an analysis of six cohorts, Dyspnoea in COVID-19 recovery beyond the ICU, ORCID record for Rodrigo Abensur Athanazio, http://creativecommons.org/licenses/by-nc/4.0/, www.ema.europa.eu/en/human-regulatory/overview/orphan-designation-overview. eCollection 2023 Jan. Liu Y, Du L, Zhu Y, Liu X, Zhou N, Li C, Li Q, He P. Acta Biochim Biophys Sin (Shanghai). A rare coincidence of Turner syndrome and bronchiectasis: A case report. Scenario: Infective exacerbation: Covers the management of an infective exacerbation of bronchiectasis.

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